Professional summary
Dr. Susheel Bhanu Busi is a molecular ecologist at the UK Centre for Ecology and Hydrology (UKCEH), specialising in multi-omics analysis and workflows. His research experience spans diverse environments, including human and animal health, freshwaters such as alpine streams and rivers, wastewater systems, and soils. Dr. Busi's prior research involves the characterisation of microbial interactions in human and environmental samples such as soils, freshwaters and wastewaters, shedding light on the distribution of composition and functional capacities of microbes within these ecosystems.
His work integrates high-throughput sequencing such as metagenomics and statistical modelling to track the functional contributions of microbial elements. He applies advanced bioinformatics workflows to characterise microbial communities and understand the ecological factors influencing gene mobility in complex systems such as soils. His research informs strategies for soil health, water quality management, pollution mitigation, antimicrobial resistance (AMR), and One Health initiatives, bridging the gap between molecular ecology and environmental science.
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Selected Publications
Grégoire Michoud, Tyler J Kohler, Hannes Peter, Jade Brandani, Susheel Bhanu Busi and Tom J. Battin (2023). Unexpected functional diversity of stream biofilms within and across proglacial floodplains despite close spatial proximity. Limnol Oceanogr. doi: 10.1002/lno.12415.
Milena Despotovic, Laura de Nies, Susheel Bhanu Busi and Paul Wilmes (2023). Reservoirs of antimicrobial resistance in the context of One Health. Current Opinion in Microbiology 73, 102291. doi: 10.1016/j.mib.2023.102291.
Susheel Bhanu Busi*, Laura de Nies*, Paraskevi Pramateftaki, Massimo Bourquin, Tyler J. Kohler, Leïla Ezzat, Stilianos Fodelianakis, Grégoire Michoud, Hannes Peter, Michail Styllas, Matteo Tolosano, Vincent De Staercke, Martina Schön, Valentina Galata, Paul Wilmes and Tom J. Battin (2023). Glacier-fed stream biofilms harbour diverse resistomes and biosynthetic gene clusters. Microb. Spectrum e04069-22. doi: 10.1128/spectrum.04069-22.
Susheel Bhanu Busi*, Massimo Bourquin*, Stilianos Fodelianakis*, Grégoire Michoud, Tyler J. Kohler, Hannes Peter, Paraskevi Pramateftaki, Michail Styllas, Matteo Tolosano, Vincent De Staercke, Martina Schön, Valentina Galata, Laura de Nies, Ramona Marasco, Daniele Daffonchio, Jade Brandani, Leila Ezzat, Paul Wilmes and Tom J. Battin (2022). Genomic and metabolic adaptations of biofilms to ecological windows of opportunities in glacier-fed streams. Nat. Commun. 13, 2168. doi:10.1038/s41467-022-29914-0.
Laura de Nies*, Susheel Bhanu Busi*, Mina Tsenkova, Rashi Halder, Elisabeth Letellier and Paul Wilmes (2022). Evolution of the murine gut resistome following broad-spectrum antibiotic treatment. Nat. Commun. 13, 2296. doi:10.1038/s41467-022-29919-9.
Massimo Bourquin*, Susheel Bhanu Busi*, Stylianos Fodelianakis, Hannes Peter, Alex Washburne, Tyler Kohler, Leïla Ezzat, Paul Wilmes and Tom J. Battin (2022). The microbiome of cryospheric ecosystems. Nat. Commun. 13, 3087. doi:10.1038/s41467-022-30816-4.
Valentina Galata*, Susheel Bhanu Busi*, Benoît Josef Kunath, Laura de Nies, Magdalena Calusinska, Rashi Halder, Patrick May, Paul Wilmes and Cédric Christian Laczny (2021). Synergistic effect of short- and long-read sequencing on functional meta-omics. Briefings in Bioinformatics, Volume 22, Issue 6, November 2021, bbab330. doi:10.1093/bib/bbab330.
Susana Martinez Arbas, Susheel Bhanu Busi, Pedro Queirós, Laura de Nies, Malte Herold, Patrick May, Paul Wilmes, Emilie E. L. Muller and Shaman Narayanasamy (2021). Challenges, Strategies, and Perspectives for Reference-Independent Longitudinal Multi-Omic Microbiome Studies. Front. Genet. 12:666244. doi:10.3389/fgene.2021.666244.
Susheel Bhanu Busi*, Paraskevi Pramateftaki*, Jade Brandani, Stilianos Fodelianakis, Hannes Peter, Rashi Halder, Paul Wilmes and Tom J. Battin (2020). Optimised biomolecular extraction for metagenomic analysis of microbial biofilms from high-mountain streams. PeerJ 8:e9973. doi:10.7717/peerj.9973.
Leïla Ezzat, Hannes Peter, Massimo Bourquin, Grégoire Michoud, Stilianos Fodelianakis, Tyler Kohler, Thomas Lamy, Susheel Bhanu Busi, Daniele Daffonchio, Nicola Deluigi, Vincent De Staercke, Ramona Marasco, Paraskevi Pramateftaki, Martina Schön, Michail Styllas, Matteo Tolosano, Paul Wilmes and Tom J. Battin (2023). Towards a global biogeography of the glacier-fed stream benthic microbiome. Preprint available at Research Square. doi: 10.21203/rs.3.rs-2697617/v1.
Selected Publications
Grégoire Michoud, Tyler J Kohler, Hannes Peter, Jade Brandani, Susheel Bhanu Busi and Tom J. Battin (2023). Unexpected functional diversity of stream biofilms within and across proglacial floodplains despite close spatial proximity. Limnol Oceanogr. doi: 10.1002/lno.12415.
Milena Despotovic, Laura de Nies, Susheel Bhanu Busi and Paul Wilmes (2023). Reservoirs of antimicrobial resistance in the context of One Health. Current Opinion in Microbiology 73, 102291. doi: 10.1016/j.mib.2023.102291.
Susheel Bhanu Busi*, Laura de Nies*, Paraskevi Pramateftaki, Massimo Bourquin, Tyler J. Kohler, Leïla Ezzat, Stilianos Fodelianakis, Grégoire Michoud, Hannes Peter, Michail Styllas, Matteo Tolosano, Vincent De Staercke, Martina Schön, Valentina Galata, Paul Wilmes and Tom J. Battin (2023). Glacier-fed stream biofilms harbour diverse resistomes and biosynthetic gene clusters. Microb. Spectrum e04069-22. doi: 10.1128/spectrum.04069-22.
Susheel Bhanu Busi*, Massimo Bourquin*, Stilianos Fodelianakis*, Grégoire Michoud, Tyler J. Kohler, Hannes Peter, Paraskevi Pramateftaki, Michail Styllas, Matteo Tolosano, Vincent De Staercke, Martina Schön, Valentina Galata, Laura de Nies, Ramona Marasco, Daniele Daffonchio, Jade Brandani, Leila Ezzat, Paul Wilmes and Tom J. Battin (2022). Genomic and metabolic adaptations of biofilms to ecological windows of opportunities in glacier-fed streams. Nat. Commun. 13, 2168. doi:10.1038/s41467-022-29914-0.
Laura de Nies*, Susheel Bhanu Busi*, Mina Tsenkova, Rashi Halder, Elisabeth Letellier and Paul Wilmes (2022). Evolution of the murine gut resistome following broad-spectrum antibiotic treatment. Nat. Commun. 13, 2296. doi:10.1038/s41467-022-29919-9.
Massimo Bourquin*, Susheel Bhanu Busi*, Stylianos Fodelianakis, Hannes Peter, Alex Washburne, Tyler Kohler, Leïla Ezzat, Paul Wilmes and Tom J. Battin (2022). The microbiome of cryospheric ecosystems. Nat. Commun. 13, 3087. doi:10.1038/s41467-022-30816-4.
Valentina Galata*, Susheel Bhanu Busi*, Benoît Josef Kunath, Laura de Nies, Magdalena Calusinska, Rashi Halder, Patrick May, Paul Wilmes and Cédric Christian Laczny (2021). Synergistic effect of short- and long-read sequencing on functional meta-omics. Briefings in Bioinformatics, Volume 22, Issue 6, November 2021, bbab330. doi:10.1093/bib/bbab330.
Susana Martinez Arbas, Susheel Bhanu Busi, Pedro Queirós, Laura de Nies, Malte Herold, Patrick May, Paul Wilmes, Emilie E. L. Muller and Shaman Narayanasamy (2021). Challenges, Strategies, and Perspectives for Reference-Independent Longitudinal Multi-Omic Microbiome Studies. Front. Genet. 12:666244. doi:10.3389/fgene.2021.666244.
Susheel Bhanu Busi*, Paraskevi Pramateftaki*, Jade Brandani, Stilianos Fodelianakis, Hannes Peter, Rashi Halder, Paul Wilmes and Tom J. Battin (2020). Optimised biomolecular extraction for metagenomic analysis of microbial biofilms from high-mountain streams. PeerJ 8:e9973. doi:10.7717/peerj.9973.
Leïla Ezzat, Hannes Peter, Massimo Bourquin, Grégoire Michoud, Stilianos Fodelianakis, Tyler Kohler, Thomas Lamy, Susheel Bhanu Busi, Daniele Daffonchio, Nicola Deluigi, Vincent De Staercke, Ramona Marasco, Paraskevi Pramateftaki, Martina Schön, Michail Styllas, Matteo Tolosano, Paul Wilmes and Tom J. Battin (2023). Towards a global biogeography of the glacier-fed stream benthic microbiome. Preprint available at Research Square. doi: 10.21203/rs.3.rs-2697617/v1.