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First year PhD student on the project "Environmental drivers of azole resistance in Aspergillus fumigatus and its relevance to human health" funded by NERC as part of Grantham Institute's Science and Solutions for a Changing Planet (SSCP) Doctoral Training Program (DTP). Co-supervised by Professor Matthew Fisher of Imperial College London and Dr Andrew Singer of Centre for Ecology and Hydrology.
Conducting a UK-wide survey of environmental Aspergillus fumigatus (Afum) by collecting air and soil samples, culturing Afum and testing for resistance to azole compounds widely used in agricultural fungicide sprays and medical drugs. Also using next-generation sequencing to explore fungal diversity in air and soil and its correlation with land use, soil type, urban vs rural and seasonality.
Currently running a citizen science project called Science Solstice to encourage members of the public from all over the U.K. to collect samples of their local air on Summer Solstice, Thursday 21st June, from which I will culture Afum and monitor for azole drug resistance.
Research Assistant (February 2015 – September 2017) – Department of Infectious Disease, Imperial College London. Working on two diverse grants and employing molecular genetics techniques on both to:
- Research global prevalence of the fungal pathogen Batrachochytrium dendrobatidis responsible for extinction events in amphibians. Lab techniques include pathogen field-isolation, sterile culturing, multiplexed PCR and TA cloning. Currently using high-throughput DNA sequencing to profile amphibian skin mycobiome and developing a bioinformatics pipeline for analysis.
- Screen a cohort of Alzheimer’s and Parkinson’s brain tissue, with age-matched controls, to investigate fungal infection as a possible risk factor for Alzheimer’s disease.
MalariaGEN Data Analyst (October 2012 - February 2015) – Wellcome Trust for Human Genetics, Oxford. Compiled and analysed a large and complex dataset consisting of clinical, genetic and immunological components collected from multiple sites across Africa and Asia, resulting in publication in Malaria Journal. Proficient in the use of statistical software “R” for analysis.