Professional summary

Holly is a Molecular Biologist in the Molecular Ecology team at UKCEH. Her research focuses on the environmental dimension of antimicrobial resistance (AMR). Holly's research interests include exploring AMR in natural and wastewater treatment environments, and particularly, investigating the effects of urban and agricultural pollution on selection and dissemination of AMR using catchment-based approaches. Recent projects she has been part of include the delivery of the UK Water Industry Research (UKWIR) Chemicals Investigation Programme (CIP) 3 investigation of AMR throughout wastewater and sludge treatment processes, and an evidence review on AMR in the environment and AMR hazard map to inform monitoring of environmental AMR in Welsh river for the Welsh Government through the Environment and Rural Affairs Monitoring and Modelling Programme (ERAMMP).

Holly has a PhD in Medical Studies from the University of Exeter with UKCEH. Her thesis was Using the microbiomes of aquatic organisms to investigate the effects of pollution on environmental AMR. She has an MRes in Molecular Microbiology from the University of Bath and a BSc in Biology from the University of Gloucestershire.

 

 

Selected publications

Stanton Isobel C. et al. , (2022), Does environmental exposure to pharmaceutical and personal care product residues result in the selection of antimicrobial-resistant microorganisms, and is this important in terms of human health outcomes?. Environmental Toxicology and Chemistry, https://setac.onlinelibrary.wiley.com/doi/10.1002/etc.5498

Sorensen James P.R. et al. , (2021), Seasonality of enteric viruses in groundwater-derived public water sources. Water Research, 207, http://dx.doi.org/10.1016/j.watres.2021.117813

Other Publications

Read, D.S., Shelton, J., Singer, A.C., Stanton, I.C. & Tipper, H.J. (2023). Antimicrobial resistance surveillance strategies within wild flora and fauna of England – Chief Scientist’s Group report. Environment Agency.

Stanton, I.C., Tipper, H.J. & Singer, A.C. (2022). Environment and Rural Affairs Monitoring & Modelling Programme (ERAMMP). ERAMMP Report-65: The development of a hazard map to inform an environmental AMR monitoring programme in Welsh rivers. Report to Welsh Government (Contract C210/2016/2017).

Hargreaves, A., Jones, V., Shipton, M., Singer, A.C., Stanton, I. & Tipper, H.J., 2022. AMR Surveillance Pilot Site Selection and Database Extension – Chief Scientist’s Group report. Environment Agency.

Tipper, H.J. & Singer, A.C., 2021. AMR in the environment – Wastewater & treatment. Society for Applied Microbiology AMR case study: AMR in the environment, Nov 2021, p.10.

Singer, A.C., Stanton, I.C., Tipper, H.J. & Read, D.S. (2021). Environment and Rural Affairs Monitoring & Modelling Programme (ERAMMP). ERAMMP Report-55: Evidence Review on the Entry and Spread of Antimicrobial Resistance (AMR) in the Rural Water Environment in Wales. Report to Welsh Government (Contract C210/2016/2017) (UK Centre for Ecology & Hydrology Projects 06297 & 06810).

Chau, K.K., Matlock, W., Constantinides, B., Lipworth, S., Newbold, L., Tipper, H.J., Goodall, T., Brett, H., Hughes, J., Crook, D.W., Eyre, D.W., Read, D.S., Walker, A.S. & Stoesser, N. Evaluation of metagenomic, 16S rRNA gene and ultra-plexed PCR-based sequencing approaches for profiling antimicrobial resistance gene and bacterial taxonomic composition of polymicrobial samples. bioRxiv, pp. 2022.05.

 

Delaney, J., Raguideau, S., Holden, J., Zhang, L., Tipper, H.J., Hill, G.L., Klümper, U., Zhang, T., Cha, C.J., Lee, K. & James, R., 2021. Impact of trimethoprim on the river microbiome and antimicrobial resistance. bioRxiv, pp.2020-06.